Preview. The data shown is representative and illustrates TotalPlanta's traceability platform.

The journey behind every bottle.

You are holding a sample of TotalPlanta's first product, a Spilanthes acmella The botanical name for jambu, an Amazonian flowering plant used in traditional medicine. oral spray. This page traces its path from an Amazonian flower to a standardized therapeutic, the way every TotalPlanta product will be traceable once in market.

Five stages. Fully documented. Open by design.

Spilanthes acmella flower
The Amazon in Para, Brazil

The Plant and the Place

Stage 01 · Origin

Spilanthes acmella, known locally as jambu, is native to the Amazon basin and grown in Para, Brazil. Our material comes from identity-confirmed flowers raised under regenerative cultivation, with sourcing structured under Brazil's access and benefit-sharing A legal framework that shares the benefits of using a country's native plants with the communities and nation they come from. framework.

Origin

Para, Brazil

Cultivar

Identity-confirmed Spilanthes acmella

Cultivation

Regenerative, cooperative-grown

Sourcing basis

Access and benefit-sharing registered

From Flower to Extract

Stage 02 · Extraction

The flowers are freeze-dried whole, then extracted with supercritical CO2 Carbon dioxide put under pressure until it behaves like a liquid solvent. It pulls compounds from the plant and leaves no chemical residue. . This two-step, solvent-free route concentrates the active compounds without heat damage and preserves the 6Z geometry The specific three-dimensional shape of the spilanthol molecule. It has to stay intact for the compound to work. that spilanthol depends on for activity.

Method

Lyophilization The technical name for freeze-drying. Water is removed by freezing to protect delicate compounds. , then scCO2 Short for supercritical CO2, the pressurized carbon dioxide used to extract the compound.

Conditions

25 to 32 MPa, 60 to 70 C

Residual solvent

None

Moisture target

Under 5%

Macro detail of a leaf surface

Stage 03 · The Compound

Spilanthol

Spilanthol is the principal bioactive The main active ingredient responsible for the plant's effects. of Spilanthes acmella. Each batch is standardized and characterized by HPLC, GC-MS, and LC-MS/MS Standard laboratory techniques that separate and identify the exact compounds in a sample. so that what is in the bottle is defined, not assumed.

Chemical name

(2E,6Z,8E)-N-isobutyl-2,6,8-decatrienamide The full scientific name that describes the molecule's exact structure.

Formula

C14H23NO

Molar mass

221.3 g/mol

logP A measure of how easily a compound moves into fatty tissue, which affects how it is absorbed.

Approx. 3.5

Standardization

At least 60% w/w Percent by weight, the share of the extract that is the active compound.

Certificate of Analysis

Representative

Spilanthol content

62.4% w/w

How much of the active compound is in the extract, measured in every batch

Identity (LC-MS/MS)

Conforms

Lab testing confirms this is the right molecule

6Z isomer integrity

Preserved

The compound kept the exact shape it needs to work

Residual solvent

None detected

No leftover chemicals from the extraction process

Moisture

4.6%

Kept dry so the extract stays stable over time

Heavy metals

Within limits

Tested safe for metals like lead and arsenic

Microbial

Within limits

Tested safe for bacteria, yeast, and mold

Stage 04 · Formulation

The Oral Spray

The standardized extract is formulated into a 5 mL oral spray designed for buccal delivery Absorbed through the lining of the cheek and mouth rather than swallowed. , where the compound acts directly at the site rather than systemically Spread through the whole body by the bloodstream. . The lead indication under development is xerostomia, the medical term for chronic dry mouth.

The sample in your hand represents this format. Final dose and excipient figures are being confirmed as formulation completes.

Product Specification

Representative

Format

5 mL amber spray, buccal

A small spray, absorbed through the lining of the mouth

Doses per bottle

Approx. 50 actuations

Roughly how many sprays each bottle holds

Spilanthol per actuation

Representative, to be confirmed

How much active compound is in each spray, being finalized

Excipients

Food-grade carrier and stabilizer

The inactive ingredients that carry and protect the compound

Storage

Low water activity, under 5% loss over 12 months

Kept dry so it stays effective on the shelf for a year

Stage 05 · Chain of Custody

Every Step, On the Record

Each batch carries a lot-linked A record tied to the specific production batch your bottle came from. record aligned to 21 CFR Part 11 A US FDA standard for keeping electronic records secure and tamper-proof. . Once in market, the QR code on every bottle opens the full chain below, from soil preparation to release, with nothing edited after the fact.

Soil preparation

Cultivation

Harvest

Whole-flower freeze-drying

Supercritical CO2 extraction

Standardization and QA

Formulation

Fill and finish

Batch release

Where We Are Today

Honest About the Stage We Are In

TotalPlanta is early. The extract is finished and in hand. The rest of the pathway is underway, and we would rather show you exactly where that stands than imply more than is true.

Complete

Purified extract

Finalized, in hand

In progress

Formulation

5 mL oral spray

In progress

Analytical validation

HPLC, GC-MS, LC-MS/MS

Planned

Clinical pathway

Proof of concept through pivotal

One Plant. A Repeatable Model.

Spilanthes acmella is the proof of concept for how TotalPlanta intends to work with every botanical that follows. Responsible sourcing, solvent-free extraction, standardization, and an open record, applied with the discipline of modern medicine.